| Date | Title | Director | Rating | Distributor | Genre |
| 09/01/2010 | My Dog Tulip | Paul Fierlinger , Sandra Fierlinger | | New Yorker Films | Animated, Adaptation |
| 09/01/2010 | The American | Anton Corbijn | R | Focus Features | Adaptation, Thriller, Romance |
| 09/03/2010 | White Wedding | Jann Turner | | Stepping Stone Pictures | Foreign, Romantic Comedy |
| 09/03/2010 | Prince of Broadway | Sean Baker | | Elephant Eye Films | Drama, Crime |
| 09/03/2010 | Going the Distance | Nanette Burstein | R | Warner Bros. Pictures Distribution | Romantic Comedy |
| 09/03/2010 | The Winning Season | James C Strouse | PG-13 | Lionsgate | Comedy, Sports |
| 09/03/2010 | Hideaway | Francois Ozon | | Strand Releasing | Drama, Foreign |
| 09/03/2010 | Machete | Robert Rodriguez , Ethan Maniquis | R | 20th Century Fox Distribution | Action |
| 09/03/2010 | Mesrine: Public Enemy Number One | Jean-Francois Richet | R | | Crime, Period, Biopic, Foreign |
| 09/03/2010 | Last Train Home | Lixin Fan | | Zeitgeist Films | Documentary, Foreign |
| 09/03/2010 | A Woman, A Gun And A Noodle Shop | Zhang Yimou | R | Sony Pictures Classics | Foreign, Comedy, Thriller, Remake, Adaptation |
| 09/03/2010 | Clear Blue Tuesday | Elizabeth Lucas | | Clear Blue Productions | Drama, Comedy, Musical |
| 09/03/2010 | We Are Family | Siddharth P. Malhotra | | UTV Motion Pictures | Drama |
| 09/10/2010 | I'm Still Here: The Lost Year of Joaquin Phoenix | Casey Affleck | | Magnolia Pictures | Documentary, Music, Biopic |
| 09/10/2010 | The Virginity Hit | Huck Botko , Andrew Gurland | R | Columbia TriStar Motion Picture Group | Comedy |
| 09/10/2010 | Sequestro | Jorge Wolney Atalla | | Paradigm | Documentary |
| 09/10/2010 | The Last Rites of Ransom Pride | Tiller Russell | R | Screen Media Ventures, LLC | Western, Action, Period |
| 09/10/2010 | Bran Nue Dae | Rachel Perkins | | Freestyle Releasing, LLC | Musical, Adaptation, Comedy |
| 09/10/2010 | Legendary | Mel Damski | PG-13 | Samuel Goldwyn Films | Family, Sports, Drama |
| 09/10/2010 | Cracks | Jordan Scott | | IFC Films | Drama, Period, Foreign |
| 09/10/2010 | Resident Evil: Afterlife | Paul W.S. Anderson | R | Sony Pictures Releasing | Sequel, Action, Thriller, Adventure, Horror |
| 09/15/2010 | Kings of Pastry | D.A. Pennebaker , Chris Hegedus | | First Run Features | Documentary |
| 09/15/2010 | Never Let Me Go | Mark Romanek | R | Fox Searchlight Pictures | Sci-Fi, Thriller, Foreign |
| 09/17/2010 | Easy A | Will Gluck | PG-13 | Sony Pictures Releasing | Comedy |
| 09/17/2010 | The Town | Ben Affleck | R | Warner Bros. Pictures Distribution | Crime, Romance, Adaptation, Drama |
| 09/17/2010 | Catfish | Henry Joost , Ariel Schulman | | Universal Pictures | Documentary, Thriller, Reality, Urban |
| 09/17/2010 | The Freebie | Kathryn Aselton | R | Phase 4 Films | Drama |
| 09/17/2010 | The Wild Hunt | Alexandre Franchi | | Hannover House | Experimental, Foreign, Thriller, Fantasy |
| 09/17/2010 | Devil | John Erick Dowdle | PG-13 | Universal Pictures | Thriller, Horror |
| 09/17/2010 | Alpha and Omega | Ben Gluck , Anthony Bell | PG | Lionsgate | Animated, Family |
| 09/21/2010 | 100 Voices: A Journey Home | Danny Gold , Matthew Asner | | NCM Fathom | Documentary, Music |
| 09/22/2010 | You Will Meet a Tall Dark Stranger | Woody Allen | R | Sony Pictures Classics | Comedy |
| 09/24/2010 | Legend of the Guardians: The Owls of Ga'Hoole | Zack Snyder | PG | Warner Bros. Pictures Distribution | Animated, Fantasy, Adaptation, Children |
| 09/24/2010 | Waiting for Superman | Davis Guggenheim | | Paramount Vantage | Documentary |
| 09/24/2010 | You Again | Andy Fickman | PG | Walt Disney Studios Motion Pictures | Comedy |
| 09/24/2010 | Genius Within: The Inner Life of Glenn Gould | Peter Raymont , Michele Hozer | | Lorber Films | Documentary, Biopic, Foreign |
| 09/24/2010 | Buried | Rodrigo Cortés | R | Lionsgate | Thriller, Mystery |
| 09/24/2010 | Wall Street 2: Money Never Sleeps | Oliver Stone | PG-13 | 20th Century Fox | Drama, Sequel |